Could neutrophilic airway inflammation in obese people be more due to obstructive sleep apnoea syndrome than to asthma?
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منابع مشابه
Could neutrophilic airway inflammation in obese people be more due to obstructive sleep apnoea syndrome than to asthma?
In a large nationwide study in Spain, BARBA et al. [1] recently reported that patients admitted for treatment of an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) over a weekend showed poorer in-hospital survival compared to those admitted on weekdays. The data suggest that this effect is independent of confounders such as age, sex, comorbidity and respiratory failure. The...
متن کاملCould neutrophilic airway inflammation in obese people be more due to obstructive sleep apnoea syndrome than to asthma?
In a large nationwide study in Spain, BARBA et al. [1] recently reported that patients admitted for treatment of an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) over a weekend showed poorer in-hospital survival compared to those admitted on weekdays. The data suggest that this effect is independent of confounders such as age, sex, comorbidity and respiratory failure. The...
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A 47 year old man with a long history of chronic loud snoring and daytime sleepiness presented with hypercapnic respiratory failure and right ventricular failure. The diagnosis of obstructive sleep apnoea (OSA) leading to the 'obesity-hypoventilation syndrome', was supported by the findings of an overnight cardio-respiratory monitoring during sleep. His symptoms and arterial blood gases improve...
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This study has investigated differences in the nocturnal sleep and daytime sleepiness among patients with obstructive sleep apnoea syndrome (OSAS), upper airway resistance (UARS), sleep hypopnoea syndrome, and normal control subjects, using sleep scoring and spectral activity analysis of the electroencephalogram (EEG). Twelve nonobese males with UARS aged 30-60 yrs were recruited. These subject...
متن کاملObstructive Sleep Apnoea Modulates Airway Inflammation and Remodelling in Severe Asthma
BACKGROUND Obstructive sleep apnoea (OSA) is frequently observed in severe asthma but the causal link between the 2 diseases remains hypothetical. The role of OSA-related systemic and airway neutrophilic inflammation in asthma bronchial inflammation or remodelling has been rarely investigated. The aim of this study was to compare hallmarks of inflammation in induced sputum and features of airwa...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2012
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00184111